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New Clinical Application Paper
Inclusive Sleep Testing: Considering Comorbidities
in HSAT

Explore our latest clinical application paper on the link between Sleep Disordered Breathing (SDB) and chronic disease. With OSA often coexisting with multiple comorbidities, inclusive HSAT solutions are essential. Learn how the Nox T3s supports comprehensive diagnostics across diverse patient populations, including those with comorbidities.

Prioritizing patient care through effective HSAT 

This resource is designed to support clinicians in selecting the most effective HSAT solutions to support diagnostic accuracy and care for diverse patient populations.

Key takeaways from the paper:

  • At least 80% of patients diagnosed with OSA also have multiple comorbidities
  • Some HSAT devices restrict use in patients with pacemakers, certain medications, or comorbid conditions

  • The Nox T3s is designed for broad clinical use with no contraindications in its intended use

  • The Nox T3s is an airflow-based HSAT with dual Nox RIP belts for advanced respiratory effort monitoring 

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What makes the Nox T3s stand out?

The Nox T3s, with its comprehensive use of airflow and respiratory effort measurements, has demonstrated reliability for diverse patient groups, including those with complex chronic conditions.

  • The Nox T3s has no contraindications, supporting diverse patient groups.
  • Findings show that AHI manually scored from Nox T3s data show close agreement with AHI from PSG, demonstrating high sensitivity and specificity for OSA severity.1-6
  • Intended for adult patients and pediatric patient populations greater than 2 years of age.
  • 24 channels (15 recorded channels, 9 derived signals).
  • Two customizable bi-polar channels (ECG, EMG, EOG, EEG).
  • 24-hour recording time with 1x AA battery and 4GB storage capacity for multiple night studies.
  • Advanced Nox RIP technology can be used as a primary airflow measurement.
  • Chain of Custody Assurance available.

1 Chang Y, Xu L, Han F, Keenan BT, Kneeland-Szanto E, Zhang R,Zhang W, Yu Y, Zuo Y, Pack AI, Kuna ST. Validation of the Nox-T3 portable monitor for diagnosis of obstructive sleep apnea in patients
with chronic obstructive pulmonary disease. J Clin Sleep Med. 2019;15(4):587–596. Https://doi.org/10.5664/jcsm.7720

2 Xu L, Han F, Keenan BT, Kneeland-Szanto E, Yan H, Dong X, Chang Y, Zhao L, Zhang X, Li J, Pack AI, Kuna ST. Validation of the Nox-T3 Portable Monitor for Diagnosis of Obstructive Sleep Apnea in Chinese Adults. J Clin Sleep Med. 2017 May 15;13(5):675-683. Doi: 10.5664/jcsm.6582.

3. Wang J, Zhang C, Xu L, et al. Home monitoring for clinically suspected obstructive sleep apnea in pregnancy. J Clin Sleep Med. Published online July 24, 2023:jcsm.10726. doi:10.5664/jcsm.10726

4. Cairns A, Wickwire E, Schaefer E, Nyanjom D. A pilot validation study for the NOX T3TM portable monitor for the detection of OSA. Sleep Breath. 2014;18(3):609-614. doi:10.1007/s11325-013-0924-2

5. Cairns AA, Wickwire EM, Schaefer E, Nyanjom D. A pilot validation study for the NOX T3 by carefusion as a screener for OSA. Sleep. 2013;36:A416.

6. Ding Q, Liu J, Wu J, et al. Validation of a portable monitor compared with polysomnography for screening of obstructive
sleep apnea in polio survivors. Front Neurol. 2023;14). doi:10.3389/ fneur.2023.1137535

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Nox RIP Technology
Foundational Piece of Every Nox Diagnostic Test

  • Patented Nox RIP belts monitor thoracic and abdominal movements, providing both a high-fidelity measurements of effort as well as a flow signal that is insensitive to mouth breathing.
  • Continuously and automatically calibrates the sum of the abdominal and thoracic signals providing accurate reflection on changes in lung volumes and airflow.
  • No-fold disposable dual belts, which have outperformed both cut-to-fit and semi-disposable RIP belts in a head-to-head comparison.1
  • Reliable backup signal for cannula flow.2,3,4
  • Single patient-use for high signal quality and hygienic operation.

1. Montazeri K, Jonsson SA, et al. The design of RIP belts impacts the reliability and quality of the measured respiratory signals.
Sleep Breath. 2021 Sep;25(3):1535-1541. doi: 10.1007/s11325-020- 02268-x. Epub 2021 Jan 7. PMID: 33411184; PMCID: PMC8376735.

2. Chang Y, Xu L, Han F, Keenan BT, Kneeland-Szanto E, Zhang R, Zhang W, Yu Y, Zuo Y, Pack AI, Kuna ST. Validation of the Nox-T3 portable monitor for diagnosis of obstructive sleep apnea in patients with chronic obstructive pulmonary disease. J Clin Sleep Med. 2019;15(4):587–596. https://doi.org/10.5664/jcsm.7720

3. Magalang UJ, Johns JN, Wood KA, Mindel JW, Lim DC, Bittencourt LR, Chen NH, Cistulli PA, Gíslason T, Arnardottir ES, Penzel T, Tufik S, Pack AI. Home sleep apnea testing: comparison of manual and automated scoring across international sleep centers. Sleep Breath. 2019 Mar;23(1):25-31. doi: 10.1007/s11325-018-1715-6.

4. Xu L, Han F, Keenan BT, Kneeland-Szanto E, Yan H, Dong X, Chang Y, Zhao L, Zhang X, Li J, Pack AI, Kuna ST. Validation of the Nox-T3 Portable Monitor for Diagnosis of Obstructive Sleep Apnea in Chinese Adults. J Clin Sleep Med. 2017 May 15;13(5):675-683. doi: 10.5664/jcsm.6582.

Customer Service That You Can Count On

Years of Experience in Sleep and Support

Many Nox customers have come to know the unprecedented support that we provide when implementing new Nox devices and Noxturnal software. Overall, we make customer support simple and straightforward.

The Nox Medical customer support team is United States-based and staffed by registered sleep technologists and experienced IT professionals. The support team is available seven days per week, 24 hours per day, by phone or email. Our support extends beyond the warranty period of the equipment for the life of the device.

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